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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. The staff are very efficient and friendly. The shower was wonderful with plenty of hot water and the whole room was very clean. The coffee shop downstairs was and added bonus. This is by far the nicest accommodation we have found in santa cruz.

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9
Wonderful
840 reviews
Price from
$50.16
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... The hotel is located in Barrio Equipetrol, a very lively upscale neighbourhood, at walking distance there are many bars and restaurants. It is also a very safe neighbourhood to walk around, even at night. The hotel is modern, rooms are spacious and well-equipped. There is also a rooftop pool with a nice view.

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9
Wonderful
442 reviews
Price from
$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Great owners and hosts. We stayed a room with a windows that opened which was helpful for a breeze. There is no air Conditioner or fans so the open window was fantastic for the breeze, birds chirping. It was a wonderful stay and would suggest it to anyone. The breakfast is homemade, delicious and expansive.

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9.2
Wonderful
272 reviews
Price from
$42.75
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. How we were welcomed by the receptionist Marcela. How Fabricio the bar tender was attentive and eager to please. How Rodrigo was great in the morning during breakfast. Just perfect. Thank you so much for this amazing experience. And again thank you to these three people mentioned above. They deserved to be rewarded.

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9.1
Wonderful
312 reviews
Price from
$102.40
per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Service was impeccable. We had to leave at 4:00 am in the morning to catch our flight and they made a full breakfast for us before we left.

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9.1
Wonderful
904 reviews
Price from
$76.64
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Beautiful place! Really quiet and relaxing and the staff was so helpful and kind. Can't recommend this place enough and we look forward to come back!

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9.2
Wonderful
115 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. We loved the charm, comfort and friendly, helpful staff.

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9.5
Exceptional
223 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Very nice. Great variety. Opened early for us as we had an early flight.

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9.4
Wonderful
393 reviews
Price from
$94.50
per night

Suite 5 Estrellas

Hotel in Santa Cruz de la Sierra

Located 1.3 miles from Gabriel Rene Moreno Autonomous University, Suite 5 Estrellas offers 5-star accommodations in Santa Cruz de la Sierra and has a garden, a restaurant and a bar.

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9.3
Wonderful
6 reviews
Price from
$28
per night

Rústico & Hotel Boutique Las Churapas

Hotel in San José de Chiquitos

Rústico & Hotel Boutique Las Churapas features an outdoor swimming pool, garden, a terrace and bar in San José de Chiquitos. The hotel provides both free WiFi and free private parking. Las Churapas is an amazing place. Owners are kind, helpful, professional, and just very relaxing to be around. The property is gorgeous. I would rather spend a week here than at any of the hotels/resorts in Santa Cruz. Basically, Aidee and Johan make their hotel feel like a peaceful retreat. I will definitely be returning!

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9.3
Wonderful
88 reviews
Price from
$38
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Most-booked hotels in Santa Cruz Region in the past month

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